abstract：AIM:To determine diagnostic rate, complications and patient tolerability of endobronchial ultrasound-guide sheath (EBUS-GS) and computed tomography (CT)-guided percutaneous core biopsy for peripheral lung lesions. METHODS:Lesions >1 cm diameter on CT were randomised to either EBUS-GS or CT-guided biopsy. Excluded were...

journal_title：Internal medicine journal

authors： Fielding DI,Chia C,Nguyen P,Bashirzadeh F,Hundloe J,Brown IG,Steinke K

更新日期：2012-08-01 00:00:00

abstract：:Clinician-performed chest ultrasound is rapidly entering clinical practice in the fields of intensive care, respiratory medicine and acute medicine. Ultrasound is clearly useful in the diagnosis and characterisation of pleural diseases. It is also critical in improving the safety of pleural interventions. More recentl...

journal_title：Internal medicine journal

authors： Hew M,Heinze S

更新日期：2012-08-01 00:00:00

abstract：:Common peroneal neuropathy (CPN) may develop unexpectedly in patients with underlying cancer. To clarify the underlying pathophysiology, clinical and neurophysiological data were prospectively collected from 10 oncology clinic patients referred for neurological assessment after the onset of foot weakness. In all patie...

journal_title：Internal medicine journal

authors： Simon NG,Kiernan MC

更新日期：2012-07-01 00:00:00

abstract：:Sleep disturbance during menopause is a common and important complaint faced by many women. There are many factors that may play a role in this problem, including vasomotor symptoms and changing hormone levels, circadian rhythm abnormalities, exacerbation of primary insomnia, mood disorders, coexistent medical conditi...

journal_title：Internal medicine journal

authors： Ameratunga D,Goldin J,Hickey M

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Escalating morbidity and mortality associated with hepatitis B virus (HBV) and hepatitis C virus (HCV) infections represent a major health burden in Australia, particularly among migrants from endemic areas who may present late. METHODS AND AIMS:We evaluated the knowledge and educational needs of general pr...

journal_title：Internal medicine journal

authors： Guirgis M,Yan K,Bu YM,Zekry A

更新日期：2012-05-01 00:00:00

abstract：:The Australian Clinical Guidelines for Stroke Management 2010 represents an update of the Clinical Guidelines for Stroke Rehabilitation and Recovery (2005) and the Clinical Guidelines for Acute Stroke Management (2007). For the first time, they cover the whole spectrum of stroke, from public awareness and prehospital ...

journal_title：Internal medicine journal

authors： Wright L,Hill KM,Bernhardt J,Lindley R,Ada L,Bajorek BV,Barber PA,Beer C,Golledge J,Gustafsson L,Hersh D,Kenardy J,Perry L,Middleton S,Brauer SG,Nelson MR,National Stroke Foundation Stroke Guidelines Expert Working Group.

更新日期：2012-05-01 00:00:00

abstract：:We describe three patients with severe refractory cutaneous polyarteritis nodosa, resulting in painful ulcers involving the lower limbs and causing toe necrosis. Due to the severity of the cutaneous manifestations, the three patients received intravenous immunoglobulins at a dose of 1 g/kg/day for 2 days monthly. Afte...

journal_title：Internal medicine journal

authors： Marie I,Miranda S,Girszyn N,Soubrane JC,Vandhuick T,Levesque H

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Current diagnostic tools are inadequate for reliable prediction of prostate cancer (PCa) aggressiveness in patients with localised disease. This results in many patients being exposed to potentially unnecessary invasive treatment and its associated morbidities. In order to develop appropriate treatment strat...

journal_title：Internal medicine journal

authors： Algotar AM,Thompson PA,Ranger-Moore J,Stratton MS,Hsu CH,Ahmann FR,Nagle RB,Stratton SP

更新日期：2012-04-01 00:00:00

abstract：:We review the aetiology of scleroderma from an epidemiological perspective examining genetic, environmental and stochastic risk factors. The presence of familial clustering (but with low twin concordance) suggests a genetic contribution, and this has been confirmed with recent candidate gene and genome-wide associatio...

journal_title：Internal medicine journal

authors： Roberts-Thomson PJ,Walker JG

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Numerous studies have shown differences in pain perception between men and women, which may affect pain management strategies. AIM:Our primary aim was to investigate whether there are gender-based differences in pain management in patients admitted to our emergency department with acute, non-specific abdomi...

journal_title：Internal medicine journal

authors： Banz VM,Christen B,Paul K,Martinolli L,Candinas D,Zimmermann H,Exadaktylos AK

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Cigarette smoking prevalence has been declining over decades in Western countries especially in higher socioeconomic groups. Employees of Australian hospitals span the socioeconomic spectrum, but there are few data on smoking prevalence from these workplaces. Because smoking is a health hazard, some argue th...

journal_title：Internal medicine journal

authors： Jones TE,Williams J

更新日期：2012-03-01 00:00:00

abstract：AIM:To ascertain the prevalence of HER2/neu-positive early breast cancer (EBC), utilisation of adjuvant trastuzumab and incidence of cardiac toxicity in a community private hospital setting. METHODS:Prospective data collected by breast oncologist and surgeons in all women diagnosed with EBC at the Mount Hospital (MH) ...

journal_title：Internal medicine journal

authors： Chan A,McGregor SR

更新日期：2012-03-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) has been described as a cause of thrombotic microangiopathy, especially thrombotic thrombocytopenic purpura (TTP). Haemolytic-uraemic syndrome (HUS) is less frequent in SLE. We report a case of such an association during an episode of severe lupus nephritis in a young woman, who was ...

journal_title：Internal medicine journal

authors： Samson M,Audia S,Leguy V,Berthier S,Janikashvili N,Martin L,Bonnotte B,Lorcerie B

更新日期：2012-01-01 00:00:00

abstract：:Lymphangioleiomyomatosis (LAM) is a rare disease affecting women, classically involving the lungs. However, extrapulmonary manifestations also occur, including renal angiomyolipomas, retroperitoneal lymphangioleiomyomas and extrathoracic lymphadenopathy. The lung disease is hormone-responsive, but no information exist...

journal_title：Internal medicine journal

authors： Sandrini A,Silverstone E,Yates DH

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Stroke neurologists, vascular surgeons, interventional neuroradiologists and interventional cardiologists have embraced carotid angioplasty and stenting (CAS) because of potential advantages over carotid endarterectomy (CEA). At Austin Health, a multidisciplinary neuro-interventional group was formed to stan...

journal_title：Internal medicine journal

authors： Mak CS,Chambers BR,Clark DJ,Molan M,Brooks M,Roberts N,Fell G,Roberts AK,New G,Donnan GA

更新日期：2011-11-01 00:00:00

abstract：:Legionella species are a common cause of community-acquired pneumonia, infrequently complicated by cavitary disease. We describe Legionella pneumophila pneumonia and abscess formation in an immunosuppressed patient receiving corticosteroid therapy for metastatic breast carcinoma. The predisposing role of corticosteroi...

journal_title：Internal medicine journal

authors： Guy SD,Worth LJ,Thursky KA,Francis PA,Slavin MA

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Patients with established coronary heart disease (CHD) are at the highest risk of further events. Despite proven therapies, secondary prevention is often suboptimal. General practitioners (GPs) are in an ideal position to improve secondary prevention. AIM:To contrast management of cardiovascular risk factor...

journal_title：Internal medicine journal

authors： Driscoll A,Beauchamp A,Lyubomirsky G,Demos L,McNeil J,Tonkin A

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Stroke is an Australian health priority area causing considerable levels of disability. We report 90-day outcomes for a cohort of acute stroke patients in New South Wales (NSW), Australia prior to randomization to a large cluster randomized controlled trial (CRCT), the Quality in Acute Stroke Care (QASC) tri...

journal_title：Internal medicine journal

authors： Middleton S,Levi C,Ward J,Grimshaw J,Griffiths R,D'Este C,Dale S,Quinn C,Evans M,Cadilhac D,McElduff P

更新日期：2011-10-01 00:00:00

abstract：:The vulnerability of older people to serious underlying medical illness and adverse effects of psychotropics means that the safe and effective treatment of severe agitation can be lifesaving, the primary management goals being to create a safe environment for the patient and others, and to facilitate assessment and tr...

journal_title：Internal medicine journal

authors： Peisah C,Chan DK,McKay R,Kurrle SE,Reutens SG

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Peptic ulcer disease risk factors have changed, as has the impact of treatment on morbidity and mortality. Recent data on clinical presentation and outcome are sparse in Australia. AIM:To determine the characteristics and outcome of patients presenting with a bleeding peptic ulcer to a tertiary referral cen...

journal_title：Internal medicine journal

authors： Halland M,Young M,Fitzgerald MN,Inder K,Duggan JM,Duggan A

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:High concentration oxygen is commonly administered during acute exacerbations of chronic obstructive pulmonary disease (AECOPD). The aim of this study was to determine the association between oxygen, severity markers and poor outcomes in AECOPD. METHODS:In an audit of patients with AECOPD arriving by ambula...

journal_title：Internal medicine journal

authors： Wijesinghe M,Perrin K,Healy B,Hart K,Clay J,Weatherall M,Beasley R

更新日期：2011-08-01 00:00:00

abstract：:Transfusion-related acute lung injury (TRALI) is a leading cause of transfusion related morbidity and mortality. Current concepts regarding the pathogenesis of this disorder imply a "two-hit" model in which neutrophils are sequestered in the pulmonary capillary bed, and subsequently activated by substances in the tran...

journal_title：Internal medicine journal

authors： Finlayson J,Grey D,Kavanagh L,Witt C

更新日期：2011-08-01 00:00:00

abstract：AIM:Premature discontinuation of antiplatelet therapy is an independent predictor of late stent thrombosis. We sought to determine the prevalence and predictors of premature discontinuation of antiplatelet therapy after drug-eluting stent implantation among patients in Asia. METHODS:A total of 207 consecutive patients...

journal_title：Internal medicine journal

authors： Poh CL,Chan MY,Lau C,Teo SG,Low AF,Tan HC,Lee CH

更新日期：2011-08-01 00:00:00

abstract：AIMS:To survey the practice among gastroenterologists in Australia relating to screening for latent infections and vaccination of patients with inflammatory bowel disease prior to treatment with tumour necrosis factor alpha (TNF-α) inhibitors. METHODS:A structured 15 question electronic survey was advertised to gastro...

journal_title：Internal medicine journal

authors： Gupta A,Macrae FA,Gibson PR

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Ageism among health professionals is increasingly recognized, but few studies investigated hospital doctors' attitudes towards older people. The aims of this study were to investigate hospital doctors' attitudes towards older people and to determine whether factors, which were identified in studies on other ...

journal_title：Internal medicine journal

authors： Leung S,Logiudice D,Schwarz J,Brand C

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Prothrombinex-VF (a three-factor prothrombin complex concentrate) contains little factor VII. Therefore, the Warfarin Reversal Consensus Guidelines from 2004 published by The Australasian Society of Haemostasis and Thrombosis recommend that it be administered with fresh frozen plasma to reverse warfarin anti...

journal_title：Internal medicine journal

authors： Tran H,Collecutt M,Whitehead S,Salem HH

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:  Several cellular pathways are implicated in the pathogenesis of pulmonary arterial hypertension (PAH) and attempts to arrest disease progression with a single drug would not be expected to succeed in the medium term. In clinical practice, combination therapy is often used in patients deteriorating on monot...

journal_title：Internal medicine journal

authors： Keogh A,Strange G,Kotlyar E,Williams T,Kilpatrick D,Macdonald P,Brown K,Pidoux A,Kermeen F,Steele P,Dalton B,Gabbay E

更新日期：2011-03-01 00:00:00

abstract：:Severe sepsis is defined as organ dysfunction in the setting of systemic inflammatory response due to infection. With changes in population age, comorbidity and the delivery of medical care, severe sepsis is increasingly common, and can present in every area of the hospital. The major obstacles to improved outcomes in...

journal_title：Internal medicine journal

authors： Huggan PJ

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:  Alcoholic liver disease (ALD) is an important contributor to the total burden of alcohol-related harm; however, the morbidity of different types of ALD in Australia has not been described. The aim of this study was to investigate recent trends in hospital admission rates among alcoholic liver cirrhosis, al...

journal_title：Internal medicine journal

authors： Liang W,Chikritzhs T,Pascal R,Binns CW

更新日期：2011-01-01 00:00:00

abstract：:Many publications have highlighted a lack of practical competencies in recently qualified interns. Consultation between the University of Queensland and the Medical Education Unit at Redcliffe Hospital identified key areas where intervention could lead to greater work readiness, and the development of a complementary ...

journal_title：Internal medicine journal

authors： Costello J,Livett M,Stride PJ,West M,Premaratne M,Thacker D

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:  Hepatic epithelioid haemangioendothelioma (HEH) is a rare, low grade malignant neoplasm of endothelial origin which is difficult to diagnose and has a variable outcome. We review five HEH cases from our centre with the aim of identifying clinical predictors of outcome and various therapeutic options. METH...

journal_title：Internal medicine journal

authors： Thin LW,Wong DD,De Boer BW,Ferguson JM,Adams L,Macquillan G,Delriviere L,Mitchell A,Jeffrey GP

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:  According to the International Prognostic Scoring System (IPSS), sole +8 is categorized as intermediate cytogenetic subgroup. But as some myelodysplastic syndrome (MDS) patients with +8 perhaps progress quickly to acute leukaemia and have shorter survival, some reports have suggested that +8 should be cate...

journal_title：Internal medicine journal

authors： Ma Y,Wang X,Xu X,Lin G

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Interstitial lung disease (ILD) and pulmonary arterial hypertension (PAH) represent the leading causes of death in systemic sclerosis (SSc). Screening for these complications has assumed greater importance, but is not universal. The aim of this study is to determine the self-reported screening, diagnosis and...

journal_title：Internal medicine journal

authors： Mangat P,Conron M,Gabbay E,Proudman SM,Pulmonary Interstitial Vascular Organisational Taskforce (PIVOT).

更新日期：2010-07-01 00:00:00

abstract：:Echocardiography is the mainstay of cardiovascular diagnostics, and is the most performed test for the evaluation of cardiac function. Critical and costly management decisions are based on quantification of left ventricular volumes and ejection fraction. Recent advances in echocardiography, such as microsphere contras...

journal_title：Internal medicine journal

authors： Hudaverdi M,Hamilton-Craig C,Platts D,Chan J,Burstow DJ

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:In 2003, chronic obstructive pulmonary disease (COPD) accounted for 46% of the burden of chronic respiratory disease in the Australian community. In the 65-74-year-old age group, COPD was the sixth leading cause of disability for men and the seventh for women. AIMS:To measure the influence of disease severi...

journal_title：Internal medicine journal

authors： Hutchinson A,Brand C,Irving L,Roberts C,Thompson P,Campbell D

更新日期：2010-05-01 00:00:00

abstract：AIM:Bigge Park Centre (BPC) is a sexual health clinic located in a socially disadvantaged area in Southwest Sydney. This served as a retrospective clinical audit, documenting patient demographics, identifying factors associated with virological, immunological and discordant responses, evaluating the centre's ability in...

journal_title：Internal medicine journal

authors： Hsu DC,Quin JW

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Secondary prevention of ischaemic stroke (IS) and transient ischaemic attack (TIA) mandates identification and treatment of multiple metabolic risk factors. The aim was to determine the prevalence of abnormal glycaemia, hypertension and dyslipidaemia in patients presenting to an Acute Stroke Unit of a tertia...

journal_title：Internal medicine journal

authors： Scott DP,Greenfield JR,Bramah V,Alford J,Bennett C,Markus R,Campbell LV

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:There is no valid cardiovascular disease (CVD) risk prediction equation for Australians with diabetes. The aim of this study is to develop and validate a multivariate risk function for 5-year cardiovascular risk prediction in Australian type 2 diabetes patients. METHODS:The Fremantle Diabetes Study is a com...

journal_title：Internal medicine journal

authors： Davis WA,Knuiman MW,Davis TM

更新日期：2010-04-01 00:00:00

abstract：:Carbimazole is a drug that is widely used for hyperthyroid disorders, such as Graves' disease. Agranulocytosis is a rare idiosyncratic adverse reaction to the drug which is potentially fatal. This report describes a patient with a history of successfully treated pyoderma gangrenosum, who developed agranulocytosis 3 we...

journal_title：Internal medicine journal

authors： Yip G,Ekinci E,Lee ST,Jerums G,Grossmann M

更新日期：2010-04-01 00:00:00

abstract：:Conventional teaching on the mechanisms and treatment of spontaneous pneumothorax is either obviously wrong or based on a misunderstanding of the natural history of the condition. Spontaneous pneumothorax is a generally benign, self-limiting condition where conservative management should be considered. If intervention...

journal_title：Internal medicine journal

authors： Simpson G

更新日期：2010-03-01 00:00:00